• Scientists Discover Allergy-Triggering Role of Peptide in the Gut

    Dec 18 | Bio-IT World | It has been firmly established in recent years that regulation of the intestinal epithelium relies heavily on signaling from epithelial, stromal, and immune cells. But there’s also a fourth player, a “very important peptide” known as VIP, which acts directly on stem cells in the gut to restrain an allergy-like response, according to Manuel Jakob, M.D., a clinician-scientist and abdominal surgeon based in Bern, Switzerland and a Ph.D. candidate at Charité -- Universitätsmedizin Berlin. More

  • Caris Life Sciences, Genentech Announce Oncology Collaboration Worth $1.1 Billion

    Dec 17 | Bio-IT World | Caris Life Sciences yesterday announced that its therapeutic research arm, Caris Discovery, has entered into a multi-year collaboration and license agreement with Genentech, a member of the Roche Group. More

  • Protein Signature Linked to Death Risk Could Aid Life Extension Efforts

    Dec 16 | Bio-IT World | A biological signal of death can be found in the blood five to 10 years in advance of that mortality outcome, a fascinating and unexpected discovery made in the quest for a signature marker of multi-morbidity by researchers at the University of Surry (UK). While by no means a clinically validated predictive test, the protein panels hold promise in motivating lifestyle changes and food choices that could change that poor health trajectory. More

  • Modeling and Shared Compute Reveals Pathways of Synthetic Drug

    Dec 12 | Bio-IT World | Researchers from the University of Illinois Urbana-Champaign used deep learning and large-scale computer simulations to identify structural differences in synthetic cannabinoid molecules that cause them to bind to human brain receptors differently from classical cannabinoids. More

  • Rethinking Precision Oncology in the Age of Functional Data

    Dec 11 | Bio-IT World | Historically, cancer treatment has relied on a one-size-fits-all approach known as the Standard of Care, where patients are treated based on population averages. But cancer is not a single disease; it’s thousands of distinct conditions, each driven by unique biology. More

  • Oxford Nanopore's Newly Named CEO Brings Diagnostics Expertise

    Dec 08 | Bio-IT World | Oxford Nanopore Technologies named a new CEO this morning, choosing an executive with extensive diagnostics experience. Francis Van Parys, currently CEO of Radiometer, will join Oxford Nanopore and the Board as an Executive Director on March 2, 2026. More

  • National University of Singapore Launches First Global Medical AI Foundation Model

    Dec 04 | Bio-IT World | Since artificial intelligence (AI) made its way into the medical field, foundation models—machine learning systems that are trained on broad data and adaptable to a wide range of downstream tasks—have become a focus. These foundation models are used to perform various medical tasks with minimal amounts of data. Of course, this means that these models require robust training, which poses a challenge for researchers. More

  • How Next-Gen Biotechnology Is Transforming Genetic Risk Prediction

    Dec 03 | Bio-IT World | As genetic testing becomes a routine part of modern medicine, researchers are grappling with an unintended consequence: a flood of never-before-seen genetic variants whose clinical significance is unknown. These variants of uncertain significance (VUS), now number in the tens of thousands, outpace the capacity of traditional scientific methods to determine whether they contribute to disease. More

  • Psychedelics and Patient Selection Tools Propelling Precision Psychiatry

    Dec 02 | Bio-IT World | How depression gets treated in the next decade is poised for significant change thanks to encouraging developments in the use of psychedelics and dissociative compounds like ketamine to alleviate symptoms of the mood disorder. Scientific interest in psychedelic-based therapies has skyrocketed in recent years, driven by promising clinical trial outcomes, a flood of financial investment, and the urgent need for new treatments to counter a growing mental health crisis More

  • Follow the Money: Enveloped Delivery Vehicle Technology, Oral Medication for Inflammatory, Neurological Diseases, More

    Nov 25 | Bio-IT World | Azalea Therapeutics will advance their Enveloped Delivery Vehicle (EDV) technology; Gate Biosciences will advance inflammatory and neurological disease treatments through the convenience of a pill; and more. More
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